You got your DNA results. Now what?
Upload the file your test provider gave you, and we'll annotate it: for every difference in your DNA, we add what's known from public databases — how common it is, what it's been linked to — so you don't have to look up each one yourself.
Supports .vcf and .vcf.gz files · Educational, never a diagnosis
What's actually in your file
Most providers hand you a VCF file — Variant Call Format. A variant is simply a small difference between your DNA and the reference human genome, the standard "template" copy scientists compare everyone against.
Imagine someone handed you a list of every word where your copy of a book differs from the original edition — page numbers, the old word, the new word — and nothing else. No note about which changes matter, which are typos, and which everybody else's copy has too. That's a raw VCF file.
For most people, that's where the service stops. The file is technically complete and practically useless.
A few lines from a typical file
#CHROM POS ID REF ALT 1 11856378 rs1801133 G A 6 26091179 rs1799945 C G 10 94781859 rs4244285 G A 12 21331549 rs4149056 T C
Every row is one difference. Nothing here tells you what any of it means — that step is called annotation, and it hasn't happened yet.
What annotation adds to your file
Annotation means matching each of your differences against what scientists have already published and adding that information to your file. To be clear about what you get back: an annotated file, not a finished medical report. The added details are technical — but they mean you can search the file for a gene or keyword and immediately see what's known about it, instead of researching every variant by hand.
How common it is
Population frequencies — how many other people carry the same difference, added as data for each variant. Many turn out to be shared by millions of people.
What it's been linked to
Database identifiers and known associations from the research literature, attached to the matching variants. How strong that evidence is varies a lot from variant to variant.
Medicine-response hints, where known
Some variants have been linked to faster or slower processing of certain common medications. The evidence varies a lot, and any medication decisions belong with your doctor.
How it works
Upload your file
Drag in your .vcf or .vcf.gz file. It goes straight into private storage that only your account can open.
We annotate it in the background
This can take a while — minutes for small files, a few hours for whole genomes. Close the tab; we'll email you the moment it's done.
Explore your annotated file
Your VCF comes back with the annotations filled in — frequencies, database IDs, known associations. Making sense of it can still take some digging, but you can search it for keywords and gene names and see what's known, right where the variant is.
How your data is handled
Genetic data is personal. Here is what happens to your file, stated plainly rather than buried in a policy.
- Your file is encrypted in storage and only reachable through your own signed-in account.
- We never sell your data, share it with insurers or employers, or use it to train anything.
- You can delete your file and every result generated from it at any time — permanently, not just hidden.
- We only email you about your own uploads. No marketing lists.
Questions people ask
Uploading a file
Uploads are tied to an account, so signing in with your email is the first step. We email you when the annotation finishes.
Sign in with email